Although rare, some people may have a serious adverse reactions to some medications that can lead to mental status alterations, fever, muscle rigidity, and changes in blood pressure, sweating, or urination. This reaction often occurs in association with starting a new anitpsychotic medication but many different types of medications can also cause it. This is an emergency and if you or a family member think you have may Neuroleptic Malignant Syndrome, you should call your medical team immediately.