Clozapine Dose Planner

This tool has been developed to assist you in thinking about the pharmacokinetics of clozapine. The information here is synthesized from clinical research studies and may not be representative of an individual patient response.

This tool is not intended to influence prescribing practices but should be used to provide an estimate of what plasma level might be obtained, given the parameters of age, gender, weight, and smoking status.

Clinical decisions should be based upon your knowledge of the patient’s situation and history and the plasma level itself, not an estimate. Clozapine levels should be drawn in the morning 12 hours after the last dose. If there is a morning clozapine dose, it should be held until the level can be drawn.
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